DIPOLE NEUROLOGY SITE IS UNDERGOING A REBUILD. LAST REPRESENTATION OF THE WORK IS THIS. CONTACT DETAILS IN PAPER. MY RESPONSE TO RATIONAL SKEPTISM IS FURTHER DOWN (BURIED UNDER MORE POSITIVE NEWS !)
Magnetic fields of radial glial in Prenates: Mechanisms for a
cortical dipole structure by VZ calcium waves
Felix Lanzalaco (a,c), Wajid Zia. (a,b)
(a) Psychology Cares Scotland, Firdon Crescent , Glasgow G15, Scotland (b) Dept of Clinical Psychology, University of Edinburgh, Scotland (c) Open University, Milton Keynes.
http://www.dipoleneurology.org.uk/__Pages/PDF/Dipole%20Neurology%20preprint%20jan%202009.pdf
PRESENTED TO
Integrative Approaches to
Brain Complexity
October 7 - 10, 2009
Organizers:
Seth Grant, Wellcome Trust Sanger Institute, UK
Nathaniel Heintz, HHMI/The Rockerfeller University, USA
Jeffrey Noebels, Baylor College of Medicine, USA
http://www.neuroscience.cam.ac.uk/news/article.php?permalink=996f8a0687
03/11/2011 FIRST LAB WORK PROVES THE VALIDITY OF THE PRIMARY PREDICTIONS
An unexpected turn in events occurred in that Vincent Fleury a French embryologist Research director at Centre National de Recherche Scientififique in Paris has developed a novel filming technique which can capture the live movements of early gestation chick embryos. Fleury has long advocated for a view of neurodevelopment first proposed by Darwin but argued against by geneticists called “structuralism”. That structure dictates gene expression rather than the other way around and is the reason most creatures are tetrapods (four-limbed forms).
The idea of structuralism is controversial and PZ myers slated Fleury initially in 2009 as “crackpot” science, with his inevitable sheeplike atheist crowd following in the unnecessary abuse. Myers is now making a quiet turnaround on this position since the death of Brian Goodwin. Richard dawkins has similarly recently conceded that structuralism may be working hand in hand with genetic expression. I do find it odd to the integrity of these science figureheads, that it takes the death of fellow colleague for them to backtrack on their insulting positions. However for those who are not dogma addicts and patient for results, recently two breakthroughs for structuralism have emerged.
Fleury used mathematical techniques to derive the conclusion that the forces he is filming in the developing brain are hydrodynamic magnetic dipole pulses, interrupted by quadrupole pulses. Anybody familiar with my work will immediately realise this is what has been predicted by dipole neurology theory. If this is not clear what this means is the dipole neurology theory now has the following.
The predicted mechanism proven by the cortex wide pulsing of calcium waves in development (see below)
Independent conformation for the spherical harmonic structure predicted for the laterical ventricles and the limbic system
Actual live lab work illustrating in motion the hydrodynamic dipole and quadrupole are present in the developing embryonic brain at the stages predicted.
This is the first movie made of this dipole force in motion.
For more information his recent paper on this is here.
http://www.epj.org/_pdf/HP_EPJE_change_in_boundary_conditions.pdfhttp://www.sciencedaily.com/releases/2011/08/110818101740.htm
Independent work finding the genetic basis for structuralism: From Blue Whales to Earthworms, a Common Mechanism Gives Shape to Living Beings ScienceDaily (Oct. 13, 2011) http://www.sciencedaily.com/releases/2011/10/111013153943.htm
08/2011 LESTER INGBER PROPOSES CORTICAL MAGNETIC MODELS READY FOR EXPERIMENTAL VERIFICATION
Dipole neurology neurodevelopment theory could not have been built without existing works proposing the key mechanism that glial cells could play in producing cortex wide magnetic fields.
Ingber & Nunez, 2010 , Bokkon & Banaclocha, 2010 , Pereira & Furlan, 2010, Střrmera & Laanec, 2009
Prof Ingber of Caltech supports the proposal that glial magnetic models are a key missing link in brain function. His primary contribution is to focus on mathematical statistical models to calculate the aggregation of these proposed magnetic interactions.
His recent paper is the best physics based summary for magnetic models, and summarizes that enough theoretical work has been completed for lab verification to begin.http://arxiv.org/abs/1105.2352
Pereira & Furlan provide a more neuroscience based overview for glial magnetic processes.
http://www.theassc.org/files/assc/PereiraJrFurlanAstrocytesHumanCognition.pdf
The above shows the proposed magnetic mechansism for cortex diple formation. Ca2+ waves in development can propogate through entire hemisphere radial glial: Weissman, TA et al; 2004.
Calcium Waves Propagate in Partial Whole-Brain Preparations
(A) Partial whole brains were prepared by removing ventral structures to open the ventricles, allowing for tissue perfusion and calcium indicator loading. Schematic shows partial whole-brain preparation and electrode placement. A, anterior; P, posterior; e, ganglionic eminence; v, ventricle; c, cortical anlage. (B) Low-magnifi cation view of Fluo-3 fl uorescence shows a mechanically stimulated calcium wave (electrode displacement of 5 µm) that propagates across the hemisphere. Higher-magnifi cation view shown in (C). Scale bar, 100 µm (B), 50 µm (C). This wave can be seen as a Supplemental Movie.
07/2011 PSEUDOSCIENCE "REVIEW" BY PAUL ALMOND AT RATIONAL SCEPTIC FORUM
Anybody searching my name may have noticed the Artificial intelligence researcher Paul Almond has posted this theory in the pseudoscience section on the rationalscepticism forum on June 26th 2011. Paul who is a senior member claims the theory is based on nothing more than brain imaging which anybody who read the paper will know is not true.
This blatant misrepresentation has very little to do with the theory and is an extension of a pre-existing political dispute I have had on going with the people who run that forum since early in 2010. That was long before they even knew who I was and that I had any scientific works. The posting and the hiking of my work to google occurred within hours of them finding my identity and was purely designed to irritate their strongest critic. Anybody who has read it will soon realise it has no bearing on the actual work itself.
The dispute with Ratskep has been such that on 30/10/2011 the forum owner Bernhard Breisser conceded my criticism had a sound basis after I stepped up my almost 2 year long campaign to illustrate the damage his members were doing to the works of competent but non mainstream scientists. He proposed that they should alter their policy on how they treat these scientific works and to rename the pseudoscience section to stop people placing scientific works in there without good reason.
I had the option given to me by the moderators to have the thread removed, because as a member of the forum the rules state another member is not allowed to post a thread criticising an existing member without that members permission. I decided to leave it online for the following reasons.
1. It illustrates that a controversy exists which is better than to be ignored, even if the work is misrepresented.
2. It’s pretty humorous and serves as a fun level advertisement for my work. But do read the serious news.
3. Their forum provides web permanence that is impossible to buy, which helps readers see the online progress.
Due to the recession as well as increasing competition for too few science jobs a proportion of the current generation have decided to acquire a general intellectual viciousness under the excuse of “rationalist” dogma. I presume this has evolved as this generation prepare a sharp frame of mind for the predicted harsh times ahead. During hard times creative advancement is often the first casualty and gang type social arrangements self organize.
This transforms science into an online sport. Yes aside from the childish insults it can be looked at as harmless pleasure (for thick skinned scientists anyway), but it is a complete misrepresentation to say that this anti-creative “rationalism” is science. I would say this is more akin to a rigid dark ages style behaviour. I hope what is going on currently is just a temporary phase, but that would be hard to predict. For anybody interested I would recommend the articles of Andrea Kusweski as a starting point for anybody who requires a modern perspective of science.
http://dipoleneurology.blogspot.com/2011/07/dipole-neurology-pseudoscience-or.html
INDEPENDENT MODEL PROPOSES SPHERICAL HARMONICS FOR LATERAL VENTRICLE DEVELOPMENT
Neurodevelopmental mathematicians Monica K. Hurdal and Deborah A. Striegel have produced a paper in September 2009 that proposes the lateral ventricles can be described in neurodevelopment by spherical harmonics. This is of course consistent with the dipole neurology 2003 Limbic EMS (electromagnetic multipole solution) model that is based on spherical harmonics for the lateral ventricles as well as all limbic system appendages. Limbic EMS was not a hypothesis I had been comfortable with but was important to publish as the limbic system would have to remain consistent with the approach taken for Cortical EMS. It is more reassuring that there is now a solid foundation from which to build a case for Limbic EMS.
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1000524
http://www.math.fsu.edu/~mhurdal/posters/hbm10prolate36x48.pdf
Its should be noted Hurdal and Streigel do not endorse Limbic or Cortex EMS. They propose the traditional view that reaction diffusion is the prime driver for cortical folding patterns rather than the MagnetoHydrodynamic (MHD) Pulsing of VZ calcium waves predicted. It should be pointed out that MHD pulsing is consistent with turing reaction /diffusion due to highly similar mathematical models which will be made clearer in a forthcoming neurodevelopmental paper for CorticoLimbic EMS.
INDEPENDENT NEUROCOMPUTATION MODELS PRODUCE TOROIDAL CONNECTIVITY
As has been stated in the paper the Cortex dipole model is asynchronous with decreased connection giving higher localized column efficiency enabled by a dipole structure that has a central toroid (see section 4 of 2009 paper). A new proposal for Ai restructuring of todays supercomputers based on neurobiology is moving towards the dipole like model by arranging each processors connectivity within a toroidal connectivity network. There has been ongoing communication with experts in AGI as to whether the dipole/linear multipolemodel can produce any predictive power or contribution to that field..
Paper : Biologically-Inspired Massively-Parallel Architectures- computing beyond a million processors
ftp://ftp.cs.man.ac.uk/pub/amulet/papers/SBF_ACSD09.pdf
Felix Lanzalaco 03/11/2011
